Live! with an AUTHOR

Dr. David Sinclair

in conversation with Heidi Legg

Recorded May 12th, 2020

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David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

David has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political risks and benefits of a world in which billions of people can live much longer and much healthier lives.

He is the co-founder of several biotechnology companies and is on the boards of several others. His first book Lifespan became a New York Times best seller in 2019.

He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time’s Top 50 in healthcare in 2018.

Visit Brookline Booksmith to have David’s book delivered right to your door.

You’re sure to enjoy this Brookline Booksmith favorite:

Lifespan: Why We Age--And Why We Don't Have to


Get ready to join David Tuesday, May 12th.

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  • 4


    On average, about how long do you spend planning on writing any one book? do you keep a writing schedule?

  • 3


    How do you think covid19 will impact longevity research and treatments moving forward?

  • 1


    Dr. Sinclair, can you please describe your process you use in your lab to identify new longevity-enhancing molecules? What are some new technologies around the corner which excite you and you believe will speed up the drug discovery process for finding new longevity molecules and/or creating personalized gene therapies for reversing human aging in the near-future?

  • 1


    When did you first know you wanted to be a scientist?

  • 0


    What impacts on our economy and environment do you foresee with an elderly population that lives longer and healthier lives?